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Imaging in living cells using νB–H Raman spectroscopy: monitoring COSAN uptake


Màrius Tarrés,  Elisabetta Canetta,  Clara Viñas,*  Francesc Teixidor and  Adrian J. Harwood*  
Chem. Commun., 2014,50, 3370-3372

DOI: 10.1039/C3CC49658A

The boron-rich cobaltabisdicarbollide (COSAN) and its 8,8′-I2 derivative (I2-COSAN), both of purely inorganic nature, are shown to accumulate within living cells, where they can be detected using νB–H Raman microspectroscopy. This demonstrates an alternative method for cell labelling and detection.


Related Topics: Biomaterials and materials for drug delivery, therapy, diagnostics and sensing

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