Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion

CrystEngComm, 2013,15, 1332-1338

DOI: 10.1039/C2CE26791H

We demonstrate how solution crystallization of lamotrigine with flexible alkane dicarboxylic acids with different chain lengths (adipic acid and pimelic acid) generates a series of four isostructural solvated three-component salts. The analysis of their crystal structures shows that isostructurality is achieved by the combination of robust hydrogen bonding motifs and the incorporation of solvent guest molecules.


Tags: Methodologies for materials science and nanotechnology

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