Synthesis of Periphery-Decorated and Core-Initiated Borane Polyanionic Macromolecules
- Scientific Highlights 30 September 2015 4657 hits
Prof. Dr. Francesc Teixidor, Dr. Ariadna Pepiol, Prof. Dr. Clara Viñas
Chemistry - A European Journal, Volume 21, Issue 30, July 20, 2015, Pages 10650–10653
A new class of globular polybranched macromolecules that contain multiple anionic metallacarborane clusters at the o-carborane periphery is reported. The water soluble high boron rich containing molecules could be of interest for boron neutron capture therapy (BNCT) as well as for drug delivery. The reinforced electrostatic noncovalent interactions between anionic polyethylene glycol cobaltabisdicarbollide (PEG-COSAN) branches and the ammonium cation have been shown using ESI-MS.
Related Topics: Bioactive materials for therapy and diagnosis