Efficient and sustainable synthesis of MOFs, as nano or microcrystalline powder, is crucial for the development of new applications for these compounds. For this purpose, the synthesis of Zn²⁺, Cu²⁺ and Fe³⁺-based MOFs was attempted in this study by using a binary medium consisting of supercritical CO₂ mixed with an ionic liquid (emimBF₄ or emimBr). In comparison with conventional solvothermal and ionothermal synthesis, MOFs were herein obtained under mild reaction conditions, i.e. 200 bar and 65 °C, after relatively short reaction periods (<10 h). To explore the described synthesis method as a generic procedure for the preparation of three-dimensional MOFs, different linkers of the imidazole and carboxylic acid families were tested. Widely investigated MOFs, such as ZIF-8 and HKUST-1, were prepared along with the complex mesoporous MIL-100(Fe). The structure and composition of the synthesized materials were determined by X-ray powder diffraction and elemental analysis. N₂ adsorption at low temperature was used to assess the textural properties.