Kiran B. Gona, Adnana Zaulet, Vanessa Gómez-Vallejo, Francesc Teixidor, Jordi Llop* and Clara Viñas*.
Chem. Commun., 2014,50, 11415-11417
A labelling method for the covalent attachment of radioiodine to the boron-rich 8-I-cobaltabisdicarbollide (I-COSAN) and a bi-functional (iodine and PEG) COSAN derivative, [3,3′-Co(8-I-1,2-C2B9H10)(8′-(OCH2CH2)2COOC6H5-1′,2′-C2B9H10)], is reported. Biodistribution studies in rodents using dissection/gamma counting and in vivo nuclear imaging have been performed. The general strategy reported here can be applied in the future to COSAN derivatives bearing a wide range of functionalities.
INSTITUT DE CIÈNCIA DE MATERIALS DE BARCELONA, Copyright © 2020 ICMAB-CSIC | Privacy Policy | This email address is being protected from spambots. You need JavaScript enabled to view it.