Bioactive materials for therapy and diagnosis

Synthesis of Periphery-Decorated and Core-Initiated Borane Polyanionic Macromolecules

30 September 2015


Prof. Dr. Francesc Teixidor, Dr. Ariadna Pepiol, Prof. Dr. Clara Viñas

Chemistry - A European Journal, Volume 21, Issue 30, July 20, 2015, Pages 10650–10653

DOI: 10.1002/chem.201501181

A new class of globular polybranched macromolecules that contain multiple anionic metallacarborane clusters at the o-carborane periphery is reported. The water soluble high boron rich containing molecules could be of interest for boron neutron capture therapy (BNCT) as well as for drug delivery. The reinforced electrostatic noncovalent interactions between anionic polyethylene glycol cobaltabisdicarbollide (PEG-COSAN) branches and the ammonium cation have been shown using ESI-MS.


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