3D Systems for immune cells culture and their applications in Immunotherapy

by Eduardo Pérez, NANOMOL Group, ICMAB-CSIC

Date: Thursday, 2 April 2020
Time: 11 am
Venue: ICMAB - Sala de Juntes (Videoconference)

Abstract: Recent achievements in the field of immunotherapy, such as the development of engineered T cells used in adoptive cell therapy, are introducing more efficient strategies to combat cancer. Nevertheless, these T cells are challenging to manufacture, manipulate, and control. Specifically, there are limitations in producing the large amounts of T cells needed for these therapies in a short period of time and in an economically viable manner. In this thesis, we have studied different 3D systems with the objective of achieving higher proliferation rates and tune the resulting phenotypes, resembling the natural environment of the secondary lymphoid organs.

Supervisor:

• Imma Ratera, NANOMOL Group, ICMAB-CSIC
• Judith Guasch, NANOMOL Group, ICMAB-CSIC

PhD Committee:

• President: Miguel Angel Mateos Timoneda, UIC campus Sant Cugat
• Secretary: Carles Mas-Moruno, Universitat Politècnica de Catalunya (UPC)
• Vocal:  Beatriz Morancho Armisen, Hospital de la Vall d’Hebron