Scientific Highlights

Recombinant Human Epidermal Growth Factor/Quatsome Nanoconjugates: A Robust Topical Delivery System for Complex Wound Healing

Lidia Ferrer-Tasies, Hector Santana, Ingrid Cabrera-Puig, Elisabet González-Mira, Lídia Ballell-Hosa, Carla Castellar-Álvarez, Alba Córdoba, Josep Merlo-Mas, Haydee Gerónimo, Glay Chinea, Viviana Falcón, Evelyn Moreno-Calvo, Jan Skov Pedersen, Jessica Romero, Claudia Navarro-Requena, Calixto Valdés, Miladys Limonta, Jorge Berlanga, Santiago Sala, Eduardo Martínez, Jaume Veciana, Nora Ventosa
A multitude of microparticles and nanoparticles is developed to improve the delivery of different small drugs and large biomolecules, which are subject to several hindering biological barriers that limit their optimal biodistribution and therapeutic effects. Here, a soft, reliable, and scalable method based on compressed CO2 is reported for obtaining nanoconjugates of recombinant human epidermal growth factor and nanovesicles called quatsomes, where the latter consists of cholesterol and cetyltrimethylammonium bromide.These nanoconjugates exhibit appropriate values of the major critical quality attributes of colloidal nanomedicines, such as controlled and narrow nanoscopic particle size distribution (which play important roles in determining their stability), drug loading, drug release, drug protection, targeting ability, and bioactivity.
Breaking News

The SCN2 organizes the 2021 Nanotechnology & Industry for PhD researchers day

On 22 June 2021, from 4 to 6:30 pm, the SCN2 (Catalan Society of Nanoscience and Nanotechnology) will celebrate the second edition of the event 'Nanotechnology and Industry for PhD researchers'.

The aim of the event is to talk about nanotechnology applied to the field of industry and business. This year the event counts with the participation of three spin-offs from ICN2, ICMAB and IMB-CNM: InBrain Neuroelectronics, Nanomol Technologies and Energiot, who will explain us their process of technology transfer.

 Front cover in “Advanced Therapeutics” for the article “Recombinant Human Epidermal Growth Factor/Quatsome Nanoconjugates: A Robust Topical Delivery System for Complex Wound Healing”.

New front cover in “Advanced Therapeutics” for the article “Recombinant Human Epidermal Growth Factor/Quatsome Nanoconjugates: A Robust Topical Delivery System for Complex Wound Healing”.


Latest News

New Cover in Advanced Therapeutics on a new scalable technology for the preparation of novel nanopharmaceuticals for wound healing

June 21, 2021
“The cover image represents a topical treatment of an open wound by spraying a suspension of nanoconjugates of a recombinant human epidermal growth factor (rhEGF) and nanovesicles, called Quatsomes, with the mission of completely and efficiently closing such an open wound with a painless therapy.” – Jaume Veciana ICMAB Researcher Jaume Veciana from the Molecular Nanoscience and Organic Materials (NANOMOL) Group is one of the authors of this article that showcases a potential nanomedicine for...
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Unit U6 NANBIOSIS at ICMAB acquires new equipment for the characterization of nanomaterials with ERDF funds

Unit U6 of NANBIOSIS (Biomaterial Processing and Nanostructuring Unit) has expanded its capabilities with two new instruments for the characterization unit. The new equipment will allow the characterization of some physico-chemical properties of different nanomaterials.

ICMAB participates in the LiOn-HD project to improve Lithium Ion Batteries

ICMAB participates in a project that wants to significantly improve the energy density, cost and sustainability of lithium-ion (Li-ion) batteries. Batteries with such improved parameters are highly sought-after in the growing electric vehicle (EV) industry.


Doctor Pau Molet with his PhD Thesis

Congratulations Dr. Pau Molet, new ICMAB Graduate

Doctor Pau Molet from the Nanostructured Materials for Optoelectronics and Energy Harvesting (NANOPTO) group at ICMAB, defended his PhD thesis titled "Managing light in optoelectronic devices with resonant optical nanostructures" on Friday, 18 June 2021 in an online session. Congrats!

Veciana & Rovira: ONLINE Workshop on research and innovation in the field of molecular materials

Finally, the workshop to honor Prof. Jaume Veciana and Prof. Concepció Rovira, from the Nanomol Group, will be an online event on Thursday, 30 September 2021. 

The cover of Advanced Therapeutics depicts a spray being applied to an infected cross section of skin.

New Cover in Advanced Therapeutics on a new scalable technology for the preparation of novel nanopharmaceuticals for wound healing

New front cover in “Advanced Therapeutics” for the article “Recombinant Human Epidermal Growth Factor/Quatsome Nanoconjugates: A Robust Topical Delivery System for Complex Wound Healing”.

Graphic for the cover (explanation on article).

New Cover in “Journal of Materials C” on chirality influenced electronic transport in molecular conductors

New Inside Cover in the Journal of Materials C for the article "Conducting chiral nickel(II) bis(dithiolene) complexes: structural and electron transport modulation with the charge and the number of stereogenic centres".


Anna Crespí, Pamela Machado, and Judith Oró at the Festa de la Ciència

An evening of science! ICMAB at the Festa de la Ciència 2021

Scientists and researchers showed experiments and gave talks through the streets of Barcelona last Sunday as the last leg of the Biennal Ciutat i Ciència de Barcelona.

A pile of multi-colored pills in someone's hands. Volodymyr Hryshchenko

A possible new world for antibiotics: boron salts against antimicrobial resistance

Researcher Clara Viñas shares the results of her investigation on boron salts in UABDivulga.


The four interviewed researchers: José Giner Planas, M. Rosa Palacín, Teresa Puig and Mariano Campoy-Quiles

#MeetTheExpert: M. Rosa Palacín, Mariano Campoy-Quiles, Teresa Puig and José Giner develop energy technologies for society

A collection of interviews to showcase the expertise in the energy field of the four groups participating at the R+D+I network XRE4S #FEDERrecerca

Banner for "Valida la teva Recerca"

Technology transfer: training and mentoring to take your research to the market

The “Valida la teva Recerca” programme offers tools to approach the transference to the market.


PhD fellows and Professors at the X Edition of the Doctoral Workshop of the PhD program in Chemistry 2021

Sohini Sinha, best Poster Prize at the UAB PhD in Chemistry Doctoral Workshop 2021 for her presentation on luminescent systems for imaging

Sohini Sinha’s presentation and poster were awarded on the 10th edition of the UAB Chemistry Doctoral Workshop 2021 with a distinguished diploma.

Raphael Pfattner and Pablo Guardia

Pablo Guardia and Raphael Pfattner awarded with a Ramón y Cajal grant #RyC

Two ICMAB researchers have been granted with a Ramón y Cajalgrant from the Spanish Ministry of Science and Innovation.

OUTREACH VIDEOS

Magnetic nanoparticles to face cancer: David against Goliath

Pablo Guardia, Ramón y Cajal researcher at ICMAB, participated on 26 May 2021 at the "Vermú de nanociencia" organized in the framework of the 10alamenos9 Nanoscience and Nanotechnology Festival.

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