by Simona Ricci, Molecular Nanoscience and Organic Materials (NANOMOL group), ICMAB, CSIC
Date: Thursday, 30 July 2020
Time: 11 am
Venue: ICMAB - Meeting Room (VIDEOCONFERENCE). Register here via Zoom.
Abstract: The development of an ultra-sensitive biosensor for the detection of α-synuclein, a biomarker of a broad range of neurodegenerative diseases, is of utmost importance. It is estimated that people suffering Parkinson’s and Alzheimer’s diseases will increase significantly in the next years. In this thesis, we developed an immunosensor for α-synuclein based on an electrolyte-gated organic field-effect transistors (EGOFETs). These devices have been recently exploited in biosensing applications thanks to their low-operating voltages, their intrinsic amplification property, low-cost of production, and possibility to fabricate them on flexible substrates. Furthermore, it was integrated into a microfluidic chamber aiming at a compact, disposable and easy to use device.
Figure: Electrolyte-gated organic field-effect transistors (EGOFETs)