Clara

Viñas Teixidor

Research Professor

Contact data:

Extension: 436242

Direct phone: 932557442

Email:

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Department: LMI

Biography

Prof. Clara Viñas graduated in Chemistry at the Universitat Autònoma de Barcelona in 1975 and in Pharmacy at the Universitat de Barcelona in 1980. She worked as a pre-doctoral student at the Prof. Rudolph’s laboratory at The University of Michigan for a year. Back to Barcelona, she worked for industry and later moved to Laboratori Municipal de Sabadell where she became the director to work on food and environmental control. She got her PhD in Pharmacy under the supervision of Prof. F. Teixidor at the Universitat de Barcelona in 1990. She joined the staff of the C.S.I.C. as tenured scientist in 1991. She promoted to research scientist in 2002 and to research professor in 2006.

Research interest

My research interests are in the design and synthesis of novel boron compounds, carboranes and metallacarboranes, to be applied in medicine, biosensors, sustainable environment and energy.

University Degrees:

Graduated in Chemistry at the Universitat Autònoma de Barcelona (U.A.B.).

Graduated in Pharmacy at the Universitat de Barcelona (U.B.).

Doctorates:

PhD in Pharmacy under the supervision of Prof. F. Teixidor at the Universitat de Barcelona in 1990.

Specialities:

Boron cluster chemistry; Nanochemistry; Gold Nanoparticles, SuperParamagnetic Nanoparticles, Bioinorganic chemistry; Nanomaterials for medicinal use; Sensors; Biosensors; Conducting Organic Polymers; Materials for Energy.

Most significative academic merits:

In June 2021, Prof. Clara Viñas was elected a member of the Academia Europaea, section of Chemistry, in celebration of her outstanding achievements as a researcher in the area of Chemistry.

Prof. Clara Viñas worked in the ”Recommendations of Nomenclature for Boranes and related species” from the IUPAC website https://iupac.org/recommendation/nomenclature-for-boranes-and-related-species/. With a fair wind it should be published in 2019. Public review ended 31 Dec 2018 IUPAC Recommendations published in PAC, AOP 19 Dec 2019; in print in Feb 2020. Pure and Applied Chemistry, 2020, 92(2), 355-381.

Awards:

Medal at the International Conference on Coordination Chemistry (ICCC42) in Brest, France on July 6th 2016.

Scientific Highlights:

I. Bennour, A.M. Cioran, F. Teixidor, C. Viñas.
“3,2,1 and Stop! An innovative, straightforward and clean route for the flash synthesis of metallacarboranes”.
Green Chemistry, 2019, 21, 1925–1928.

E. Oleshkevich, A. Morancho, A. Saha, K. M. O. Galenkamp, A. Grayston, S. Gennatti Crich, D. Alberti, N. Protti, J. X. Comella, F. Teixidor A. Rosell and C. Viñas.
“Combining Magnetic Nanoparticles and Icosahedral Boron Clusters in Biocompatible Inorganic Nanohybrids for Cancer Therapy”.
Nanomedicine: Nanotechnology, Biology and Medicine, 20 (2019) 101986.

Z. Kelemen, A. Pepiol, M. Lupu, R. Sillanpää, M. M. Hänninen, F. Teixidor, C. Viñas.

“Icosahedral carboranes as scaffolds for congested regioselective polyaryl compounds. The distinct distance tuning of C-C and its antipodal B-B”.

Chemical Communications, 2019, 55, 8927 – 8930.

Back cover of the issue.

D.C. Malaspina, C. Viñas, F. Teixidor, J. Faraudo.

“Atomistic simulations of COSAN: amphiphiles without a Head‐and‐Tail design have a “head and tail” surfactant behavior”.

Angewandte Chemie International Edition, 2020, 59, 3088 –3092.

- Destacado por la periodista científica Katrina Kramer de la revista inglesa Chemistry World de la RSCPublising en diciembre del 2019.

https://www.chemistryworld.com/news/mystery-around-stealthy-surfactants-deepens-as-study-raises-more-questions/4010979.article

Jordi Poater, Clara Viñas, Ines Bennour, Sílvia Escayola, Miquel Solà, and Francesc Teixidor.

“Too Persistent to Give Up: Aromaticity in Boron Clusters Survives Radical Structural Changes.”

Journal of the American Chemical Society, 2020, 142, 9396−9407. DOI: 10.1021/jacs.0c02228.

Frontal cover of the issue.

Highlighted in: Spotlights on Recent JACS Publications doi/pdf/10.1021/jacs.0c05957.

Marcos Couto, Catalina Alamón, María Fernanda García, Mariángeles Kovacs, Emiliano Trias, Susana Nievas, Emiliano Pozzi, Paula Curotto, Silvia Thorp, María Alejandra Dagrosa, Francesc Teixidor, Clara Viñas and Hugo Cerecetto.

“Closo-carboranyl- and Metallacarboranyl[1,2,3]triazolyl-decorated Lapatinib-scaffold for Cancer Therapy Combining Tyrosine Kinase Inhibition and Boron Neutron Capture Therapy.”

Cells, 2020, 9, 1408; doi:10.3390/cells9061408.

Isabel Romero García, Isabel Guerrero, Arpita Saha Jewel Ann Maria Xavier, Clara Viñas, Francesc Teixidor.

“Non-covalently Linked Metallacarboranes on Functionalized Magnetic Nanoparticles as Highly Efficient, Robust and Reusable Photocatalysts in Aqueous Medium.”

ACS Applied Materials & Interfaces, 2020 12 (50), 56372-56384. DOI: 10.1021/acsami.0c17847.

Isabel Romero, Margarita Martinez-Medina, Carla Camprubí-Font, Ines Bennour, David Moreno, Luis Martínez-Martínez, Francesc Teixidor, Mark A. Fox, Clara Viñas.

“Metallacarborane assemblies as effective antimicrobial agents including a highly potent anti-MRSA agent.”

Organometallics, 2020, 39, 4253-4264.

Supplementary cover of the issue.

C. Alamón, B. Dávila, M. F. García, C. Sánche, M. Kovacs, E. Trias, L. Barbeito, M. Gabay, N. Zeineh, M. Gavish, F. Teixidor, C. Viñas, M. Couto and H. Cerecetto.

“Sunitinib containing carborane pharmacophore with ability to inhibit tyrosine kinases receptors, FLT3, KIT, and PDGFR-β, exhibits powerful in vivo anti-glioblastoma activity”.

Cancers, 2020, 12, 3423; doi:10.3390/cancers12113423

A. B. Buades, V. S. Arderiu, D. Olid-Britos, C. Viñas, R. Sillanpää, M. Haukka, X. Fontrodona, M. Paradinas, C. Ocala and F. Teixidor.

"Electron accumulative molecules".

Journal of the American Chemical Society, 2018, 140, 8, 2957-2970. DOI: 10.1021/jacs.7b12815.

M. Couto, M. Fernanda García, C. Alamón, M. Cabrera, P. Cabral, A. Merlino, F. Teixidor, H. Cerecetto* and C. Viñas*.

"Discovery of potent EGFR inhibitors through the incorporation of a 3D-aromatic-boron-rich-cluster into the 4-anilinoquinazoline scaffold: Potential drugs for glioma treatment".

Chemistry-A European Journal, 2018, 24, 3122 – 3126. DOI: 10.1002/chem.201705181.

Hot paper. Issue frontal back cover.

M. P. Grzelczak, S. P. Danks, R. Klipp, D. Belic, A. Zaulet, C. Kunstmann-Olsen, D. F. Bradley, T. Tsukuda, C. Viñas, F. Teixidor, J. Abramson and M. Brust.

"Ion transport across biological membranes by carborane-capped gold nanoparticles".

ACS Nano 2017, 11, 12492−12499.

A. Saha, E. Oleshkevich, C. Vinas, F. Teixidor.

Biomimetic Inspired Core-Canopy Quantum Dots: Ions Trapped in Voids Induce Kinetic Fluorescence Switching.

Advanced Materials, 2017, 29, 1704238- 1704245.

M. Couto, I. Mastandrea, M. Cabrera, P. Cabral, F. Teixidor, Hugo Cerecetto* and C. Viñas *.

Small-molecule Kinase Inhibitors-loaded Boron Cluster as Hybrid Agents for Glioma Cell-targeting Therapy.

Chemistry-A European Journal, 2017, 23, 9233 – 9238. DOI: 10.1002/chem.201701965.

Destacado por la revista como Hot Paper. Frontispiece article. Fué escogido para ser destacado en ChemistryViews website

http://www.chemistryviews.org/details/ezine/10599447/Dual-Action_Drugs_Hybridized_Boron-Rich_Clusters.html

T. García-Mendiola, V. Bayon-Pizarro, A. Zaulet, F. Pariente, I. Fuentes, C. Viñas*, F. Teixidor and E. Lorenzo*.

"Metallacarboranes as tunable redox potential electrochemical tools for screening of gene mutation"

Chemical Science, 2016, 7, 5786-5797.

R. Núñez, M. Romero, F. Teixidor. C. Viñas*.

"Icosahedral Boron Cluster: a perfect tool for the enhancement of polymer features"

Chemical Society Reviews, 2016, 45(19), 5137-5434.

Issue frontal cover. Según los datos de Essential Science Indicators del Web of Science: desde Septiembre/Octubre de 2017, este artículo muy citado recibió suficientes citas para incluirse en el 1% de los mejores artículos del campo académico de Chemistry en función de un umbral de artículos muy citados para el campo y el año de publicación.

Destacado por ChemInform en Noviembre 2016.

M. Tarrés, E. Canetta, E. Paul, J. Forbes, K. Azzouni, C. Viñas*, F. Teixidor, A. J. Harwood

“Biological interaction of COSAN-based synthetic vesicles with living cells”.

Scientific Reports, 2015, 5: 7804. DOI: 10.1038/srep07804.

K. B. Gona, A. Zaulet, V. Gómez-Vallejo, F. Teixidor, J. Llop* and C. Viñas*

“COSAN as a molecular imaging platform: Synthesis and “in vivo” imaging”.

Chemical Communications, 2014, 50 (77), 11415 – 11417. DOI: 10.1039/c4cc05058d.

Archive for the ‘Hot Articles’ Category at the web. http://blogs.rsc.org/cc/category/hot-article/page/2/

Dr. Laura Fisher, Publishing Editor: Soft Matter, Polymer Chemistry and Biomaterials Science of the Royal Society of Chemistry, wrote an article for Chemistry World about the article (http://www.rsc.org/chemistryworld/2014/08/radiolabel-boron-neutron-capture-therapy-iodine).

C. Verdiá-Báguena, A. Alcaraz, V. M. Aguilella, A. M. Cioran, S. Tachikawa, H. Nakamura, F. Teixidor and C. Viñas*

“Amphiphilic COSAN and I2-COSAN crossing synthetic lipid membranes: planar bilayers and liposomes”.

Chemical Communications, 2014, 50, 6700-6703.

Portada frontal del issue.

Prof. Jeff Green, de la University of Sheffield, destacó este artículo el 10 de Octobre del 2014 en la web de Crossing Biological Membranes Network (CBMNet); http://cbmnetnibb.group.shef.ac.uk/test/

A.R. Popescu, F Teixidor, C Viñas*.

“Metal Promoted Charges and Hapticities of Phosphines: The Uniqueness of Carboranylphosphines.”

Coordination Chemistry Reviews, 269 (2014) 54–84.

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