![Aromaticity and Extrusion of Benzenoids Linked to [o-COSAN]−: Clar Has the Answer](/templates/yootheme/cache/c7/toc-clara-1-c74ca3f4.jpeg)
Clar has the answer! Clar's π-sextets justify the reason why the linked system of [o-COSAN]− and benzenoid drives to extrusion in the case of naphthalene or anthracene, but not for benzene, pyrene or perylene. Benzene and pyrene can be synthetically linked to [o-COSAN]− keeping their aromaticity. In contrast, naphthalene and anthracene are extruded in the same reaction. We have proven that extrusion is only favorable if the number of Clar's π-sextets remains constant. Thus, Clar has the answer to whether an attached polycyclic aromatic hydrocarbon to [o-COSAN]− is extruded or not.
Clar has the answer! Clar's π-sextets justify the reason why the linked system of [o-COSAN]− and benzenoid drives to extrusion in the case of naphthalene or anthracene, but not for benzene, pyrene or perylene. Benzene and pyrene can be synthetically linked to [o-COSAN]− keeping their aromaticity. In contrast, naphthalene and anthracene are extruded in the same reaction. We have proven that extrusion is only favorable if the number of Clar's π-sextets remains constant. Thus, Clar has the answer to whether an attached polycyclic aromatic hydrocarbon to [o-COSAN]− is extruded or not.
Bioactive materials for therapy and diagnosis
Aromaticity and Extrusion of Benzenoids Linked to [o-COSAN]−: Clar Has the Answer
Prof. Dr. Jordi Poater, Prof. Dr. Clara Viñas, Dr. David Olid, Prof. Dr. Miquel Solà, Prof. Dr. Francesc Teixidor
Angew. Chem.Int. Ed. 2022, 61, e202200672
DOI: https://doi.org/10.1002/anie.202200672
