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M4HTH Smart Nanomedicine

Enhancing the Antimicrobial Photodynamic Activity of Heteroleptic Ruthenium(II) Complexes: Role of Asymmetric N-Donor-Based Ligands

A new paper has been

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Quatsomes as versatile fluorescent nanocarriers: stable Eosin Y loading and FRET with a membrane dye

A new paper has been

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Self-induced dimensional reduction and scaling transition of mRNA in polysomes: A multiscale simulation study

A new paper has been

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STORM as a tool to track cargo release from polymeric nanocarriers at the single-particle level

A new paper has been

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Single-Gland-Level Sweat Sampling: A Theoretical and Computational Approach Toward Improved Biomarker Accuracy in Wearable Sensors

A new paper has been

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Designing Water-Soluble Macromolecules for Biomedical Use: PEG Chains versus Amino Acids─A Case Study in MRI Contrast Agents

A new paper has been

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Dual-Function Electrocatalytic Activity Unleashed by FeMo-Graphdiyne@Ni3S2 with Engineered Heterointerfaces

A new paper has been

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Stable ultrabright nanoprobes for two-photon excitation microscopy based on octupolar merocyanine-loaded nanovesicles

A new paper has been

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Stabilizing Anion–Anion Aggregates via Dihydrogen Bonds in Non-Classical Inorganic Molecules

A new paper has been

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Intrinsically Chiral Excimers: Water-Compatible Trityl-Based Nanoparticles as Tailored Dual Emitters of Circularly Polarized Luminescence in the Vis or NIR Regions

A new paper has been

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Probing the Structural Dynamics of the Unbound MAX Protein: Insights from Well-Tempered Metadynamics

A new paper has been

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Plasmid DNA Delivery Using a Stable Nanovesicle Platform: A Design-of-Experiments-Guided Investigation

A new paper has been

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Carborane-BODIPY dyes as promising photosensitizers for light-mediated antimicrobial strategies

A new paper has been

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Narrow-Diameter Tubular One-Dimensional van der Waals Heterostructures

A new paper has been

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Targeted PET Imaging of Atherosclerosis via Low-Density Lipoprotein Click Chemistry with Nanoparticles

A new paper has been

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2Danalysis: A toolbox for analysis of lipid membranes and biopolymers in two-dimensional space

A new paper has been

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Beyond M1/M2: The role of reactive oxygen species in liver fibrosis and immune modulation

A new paper has been

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Deconstructing biomineralization codes: a high throughput microfluidic material genome strategy for calcium carbonate crystallization

A new paper has been

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Brominated trityl radical nanoparticles: metal-free ratiometric nanothermometer with near-infrared excimeric emission in water

A new paper has been

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Comparative in vivo PET imaging of silica microparticles: shape-dependent blood circulation and short-term biodistribution

A new paper has been

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Polyoxometalate-based Cu(II) complexes as the photocatalyst for oxidation of toluene and photodegradation of metronidazole

A new paper has been

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Titanium dioxide@polyoxometalate-organic framework as an efficient photocatalyst for dye degradation under visible light conditions

A new paper has been

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Eco-Friendly Conformal and Self-Adhesive Electrochemical Sensors for Sweat Monitoring

A new paper has been

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Anionic Boron-Cluster BODIPY Conjugates As Promising Photosensitizers for Targeted Antimicrobial Photodynamic Therapy

A new paper has been

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Noninvasive cardiac modulation via triplet-sensitized photoswitching in the phototherapeutic window

A new paper has been

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Influence of local ordering in the permeation of Temozolomide through the brain plasmatic membrane

A new paper has been

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Enhancing Boron Neutron Capture Therapy (BNCT) with Materials Based on COSAN-Functionalized Nanoparticles

A new paper has been

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Lymph-Node Inspired Hydrogels Enhance CAR Expression and Proliferation of CAR T Cells

A new paper has been

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Activating Thermoplastic Polyurethane Surfaces with Poly(ethylene glycol)-Based Recombinant Human α-Defensin 5 Monolayers for Antibiofilm Activity

A new paper has been

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Biodistribution of 89Zr-Radiolabeled Nanoassemblies for Monoclonal Antibody Delivery Revealed through In Vivo PET Imaging

A new paper has been

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TEMPO radical-functionalized amphiphilic dendritic structures as metal-free MRI contrast agents from fibers to nanoparticles

A new paper has been

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Synthesis and Relaxivity study of amino acid-branched radical dendrimers as MRI contrast agents for potential brain tumor imaging

A new paper has been

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Targeted nanoliposomes to improve enzyme replacement therapy of Fabry disease

  • Título : Targeted nanoliposomes to improve enzyme replacement therapy of Fabry disease
  • Autores: Judit Tomsen Melero, Marc Moltó Abad, Josep Merlo-Mas , Zamira V. Díaz-Riascos , Edgar Cristóbal-Lecina , Andreu Soldevila, Thomas Altendorfer-Kroath, Dganit Danino, Inbal Ionita, Jan Skov Pedersen, Lyndsey Snelling, Hazel Clay, Aida Carreño, José L. Corchero, Daniel Pulido, Josefina Casas, Jaume Veciana, Simó Schwartz Jr., Santi Sala, Albert Font, Thomas Birngruber, Miriam Royo, Alba Córdoba, Nora Ventosa, Ibane Abasolo, and Elisabet González-Mira
  • Citation and DOI:

    Science Advances, Vol 10, Issue 50

    DOI: 10.1126/sciadv.adq4738

  • PlumX: Targeted nanoliposomes to improve enzyme replacement therapy of Fabry disease 

A new paper has been

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Supercritical CO2 assisted bioMOF drug encapsulation and functionalization for delivery with a synergetic therapeutic value

A new paper has been

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3D Printing as a Strategy to Scale-Up Biohybrid Hydrogels for T Cell Manufacture

A paper on biohybrid

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Compelling DNA intercalation through ‘anion–anion’ anti-coulombic interactions: boron cluster self-vehicles as promising anticancer agents

A new paper on boron

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In situ shaping of intricated 3D bacterial cellulose constructs using sacrificial agarose and diverted oxygen inflow

Efficient Nebulization and Pulmonary Biodistribution of Polymeric Nanocarriers in an Acute Lung Injury Preclinical Model

A new article has been

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Developing photo-activable ruthenium (II) complexes for PDT: Synthesis, characterization, photophysical and biological studies

The easy tunable

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Caenorhabditis elegans endorse bacterial nanocellulose fibers as functional dietary Fiber reducing lipid markers

Bacterial ...

Nanothermometer Based on Polychlorinated Trityl Radicals Showing Two-Photon Excitation and Emission in the Biological Transparency Window: Temperature Monitoring of Biological Tissues

Nanothermometers are...

Towards the Application of Purely Inorganic Icosahedral Boron Clusters in Emerging Nanomedicine

Traditionally, drugs were...

Arrhythmic Effects Evaluated on Caenorhabditis elegans: The Case of Polypyrrole Nanoparticles

Experimental studies and...

Cell-Laden 3D Hydrogels of Type I Collagen Incorporating Bacterial Nanocellulose Fibers

There is a growing interest...

A Potential Boron Neutron Capture Therapy Agent Selectively Suppresses High-Grade Glioma: In Vitro and in Vivo Exploration

Glioblastoma (GBM), as the...

Ce1−xZrxO2 nanoparticles in bacterial cellulose, bio-based composites with self-regenerating antioxidant capabilities

Bacterial cellulose (BC) is...

Antibiofilm surfaces based on the immobilization of a novel recombinant antimicrobial multidomain protein using self-assembled monolayers

The constant increase of...

Conductive Bacterial Nanocellulose-Polypyrrole Patches Promote Cardiomyocyte Differentiation

The low endogenous...

Ratiometric Nanothermometer Based on a Radical Excimer for In Vivo Sensing

Ratiometric fluorescent...

Interaction-Limited Aggregation: Fine-Tuning the Size of pNIPAM Particles by Association with Hydrophobic Ions

We have investigated the...

Lithium halide filled carbon nanocapsules: Paving the way towards lithium neutron capture therapy (LiNCT)

Neutron capture therapy...

Facile, fast and green synthesis of a highly porous calcium-syringate bioMOF with intriguing triple bioactivity

A facile, fast and green

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Bioengineered extracellular vesicles: future of precision medicine for sepsis

Sepsis is a syndromic...

Quatsomes Loaded with Squaraine Dye as an Effective Photosensitizer for Photodynamic Therapy

Photodynamic therapy is a...

Boron clusters (ferrabisdicarbollides) shaping the future as radiosensitizers for multimodal (chemo/radio/PBFR) therapy of glioblastoma

Glioblastoma multiforme

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Key Parameters for the Rational Design, Synthesis, and Functionalization of Biocompatible Mesoporous Silica Nanoparticles

Over the last few years,...

Hierarchical Quatsome-RGD Nanoarchitectonic Surfaces for Enhanced Integrin-Mediated Cell Adhesion

  • Título : Hierarchical Quatsome-RGD Nanoarchitectonic Surfaces for Enhanced Integrin-Mediated Cell Adhesion
  • Autores: Marc Martínez-Miguel, Miquel Castellote-Borrell, Mariana Köber, Adriana R. Kyvik, Judit Tomsen-Melero, Guillem Vargas-Nadal, Jose Muñoz, Daniel Pulido, Edgar Cristóbal-Lecina, Solène Passemard, Miriam Royo, Marta Mas-Torrent, Jaume Veciana, Marina I. Giannotti, Judith Guasch, Nora Ventosa*, and Imma Ratera*
  • Citation and DOI:
    ACS Appl. Mater. Interfaces 2022, 14, 42, 48179–48193
    Publication Date:October 17, 2022
    https://doi.org/10.1021/acsami.2c10497
  • PlumX: Hierarchical Quatsome-RGD Nanoarchitectonic Surfaces for Enhanced Integrin-Mediated Cell Adhesion
The synthesis and study of...

Stable nanovesicles formed by intrinsically planar bilayers

  • Título : Stable nanovesicles formed by intrinsically planar bilayers
  • Autores: Mariana Köberb, Sílvia Illa-Tuseta, LidiaFerrer-Tasies, Evelyn Moreno-Calvo, Witold I. Tatkiewicz, Natascia Grimaldi, David Piña, Alejandro Pérez Pérez, Vega Lloveras, JoséVidal-Gancedo, Donatella Bulone, Imma Ratera, Jan Skov Pedersen, Dganit Danino, Jaume Veciana, Jordi Faraudo, Nora Ventosa
  • Citation and DOI:

    Journal of Colloid and Interface Science Volume 631, Part A, February 2023, Pages 202-211

    https://doi.org/10.1016/j.jcis.2022.10.104

  • PlumX: Stable nanovesicles formed by intrinsically planar bilayers
Hypothesis...

Liposomal formulations for treating lysosomal storage disorders

Lysosomal storage disorders...

Ultrabright Föster Resonance Energy Transfer Nanovesicles: The Role of Dye Diffusion

The development of contrast...

Supramolecular Hydrogels Consisting of Nanofibers Increase the Bioavailability of Curcuminoids in Inflammatory Skin Diseases

The low bioavailability of...

How to switch from a poor PEDOT:X oxygen evolution reaction (OER) to a good one. A study on dual redox reversible PEDOT:metallacarborane

Over the years, extensive...

Molecular Dynamics Simulations of Adsorption of SARS-CoV-2 Spike Protein on Polystyrene Surface

A prominent feature of...

Metal-Free Radical Dendrimers as MRI Contrast Agents for Glioblastoma Diagnosis: Ex Vivo and In Vivo Approaches

Simultaneously being a...

Quatsomes Formulated with l-Prolinol-Derived Surfactants as Antibacterial Nanocarriers of (+)-Usnic Acid with Antioxidant Activity

The efficacy of the...

Highly Aligned Bacterial Nanocellulose Films Obtained During Static Biosynthesis in a Reproducible and Straightforward Approach

Bacterial nanocellulose...

One-step double network hydrogels of photocurable monomers and bacterial cellulose fibers

Soft-tissue replacements are...

3D and 2D aromatic units behave like oil and water in the case of benzocarborane derivatives

A large number of 2D/2D and...

Enhanced human T cell expansion with inverse opal hydrogels

Advanced personalized...

Water-Stable Carborane-Based Eu3+/Tb3+ Metal–Organic Frameworks for Tunable Time-Dependent Emission Color and Their Application in Anticounterfeiting Bar-Coding

Luminescent lanthanide...

Water soluble organometallic small molecules as promising antibacterial agents: synthesis, physical–chemical properties and biological evaluation to tackle bacterial infections

The...

Aromaticity and Extrusion of Benzenoids Linked to [o-COSAN]−: Clar Has the Answer

Clar has the answer!

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Exploring the impact of the recombinant Escherichia coli strain on defensins antimicrobial activity: BL21 versus Origami strain

The growing emergence of...

Riboflavin–citrate conjugate multicore SPIONs with enhanced magnetic responses and cellular uptake in breast cancer cells

Breast cancer accounts for...

o-Carborane-based fluorophores as efficient luminescent systems both as solids and as water-dispersible nanoparticles

A set...

Pushing the Limits on the Intestinal Crossing of Metal–Organic Frameworks: An Ex Vivo and In Vivo Detailed Study

Biocompatible nanoscaled...

Multifunctional Switch Based on Spin-Labeled Gold Nanoparticles

The fabrication of...

Induced ligno-suberin vascular coating and tyramine-derived hydroxycinnamic acid amides restrict Ralstonia solanacearum colonization in resistant tomato

Tomato varieties resistant...

Magnetic Mesoporous Silica Nanorods Loaded with Ceria and Functionalized with Fluorophores for Multimodal Imaging

Multifunctional magnetic...

1.3 V Inorganic Sequential Redox Chain with an All-Anionic Couple 1–/2– in a Single Framework

The relatively low symmetry...

Dramatic Drop in Cell Resistance through Induced Dipoles and Bipolar Electrochemistry

The use of slurries of...

Light-Induced On/Off Switching of the Surfactant Character of the o-Cobaltabis(dicarbollide) Anion with No Covalent Bond Alteration

Quantum chemistry reveals

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Cobaltabis(dicarbollide) ([o-COSAN]−) as Multifunctional Chemotherapeutics: A Prospective Application in Boron Neutron Capture Therapy (BNCT) for Glioblastoma

Purpose: The aim of our...

Ultrafast Interface Charge Separation in Carbon Nanodot–Nanotube Hybrids

  • Título : Ultrafast Interface Charge Separation in Carbon Nanodot–Nanotube Hybrids
  • Autores: Alice Sciortino*, Francesco Ferrante, Gil Gonçalves, Gerard Tobias, Radian Popescu, Dagmar Gerthsen, Nicolò Mauro, Gaetano Giammona, Gianpiero Buscarino, Franco M. Gelardi, Simonpietro Agnello, Marco Cannas, Dario Duca, and Fabrizio Messina*
  • Citation and DOI:
    ACS Appl. Mater. Interfaces 2021, 13, 41, 49232–49241
    Publication Date:October 5, 2021
    DOI: https://doi.org/10.1021/acsami.1c16929
  • PlumX: Ultrafast Interface Charge Separation in Carbon Nanodot–Nanotube Hybrids
Carbon dots are an emerging...

Polylactide, Processed by a Foaming Method Using Compressed Freon R134a, for Tissue Engineering

Fabricating polymeric...

Endovascular administration of magnetized nanocarriers targeting brain delivery after stroke

The increasing use of...

Synchrotron-Based Fourier-Transform Infrared Micro-Spectroscopy (SR-FTIRM) Fingerprint of the Small Anionic Molecule Cobaltabis (dicarbollide) Uptake in Glioma Stem Cells

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Engineering DNA-Grafted Quatsomes as Stable Nucleic Acid-Responsive Fluorescent Nanovesicles

The development of...

Induced Dipoles and Possible Modulation of Wireless Effects in Implanted Electrodes. Effects of Implanting Insulated Electrodes on an Animal Test to Screen Antidepressant Activity

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Nanocarbon-Iridium Oxide Nanostructured Hybrids as Large Charge Capacity Electrostimulation Electrodes for Neural Repair

Nanostructuring nanocarbons...

Iridium Oxide Redox Gradient Material: Operando X‑ray Absorption of Ir Gradient Oxidation States during IrOx Bipolar Electrochemistry

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Bias-Polarity-Dependent Direct and Inverted Marcus Charge Transport Affecting Rectification in a Redox-Active Molecular Junction

This paper describes the...

Ru(II) and Ir(III) phenanthroline-based photosensitisers bearing o-carborane: PDT agents with boron carriers for potential BNCT

Four novel transition...

Recombinant Human Epidermal Growth Factor/Quatsome Nanoconjugates: A Robust Topical Delivery System for Complex Wound Healing

A multitude of...

Impact of Chemical Composition on the Nanostructure and Biological Activity of α-Galactosidase-Loaded Nanovesicles for Fabry Disease Treatment

  • Título : Impact of Chemical Composition on the Nanostructure and Biological Activity of α-Galactosidase-Loaded Nanovesicles for Fabry Disease Treatment
  • Autores: Judit Tomsen-Melero, Solène Passemard, Natalia García-Aranda, Zamira Vanessa Díaz-Riascos, Ramon González-Rioja, Jannik Nedergaard Pedersen, Jeppe Lyngsø, Josep Merlo-Mas, Edgar Cristóbal-Lecina, José Luis Corchero, Daniel Pulido, Patricia Cámara-Sánchez, Irina Portnaya, Inbal Ionita, Simó Schwartz Jr., Jaume Veciana, Santi Sala, Miriam Royo, Alba Córdoba, Dganit Danino, Jan Skov Pedersen, Elisabet González-Mira*, Ibane Abasolo*, and Nora Ventosa*
  • Citation and DOI:
    ACS Appl. Mater. Interfaces 2021, XXXX, XXX, XXX-XXX
    Publication Date:February 14, 2021
    DOI: https://doi.org/10.1021/acsami.0c16871
  • PlumX: Impact of Chemical Composition on the Nanostructure and Biological Activity of α-Galactosidase-Loaded Nanovesicles for Fabry Disease Treatment
Fabry disease is a rare...

Radiolabeled Cobaltabis(dicarbollide) Anion–Graphene Oxide Nanocomposites for In Vivo Bioimaging and Boron Delivery

A carbon-based hybrid...

Sunitinib-Containing Carborane Pharmacophore with the Ability to Inhibit Tyrosine Kinases Receptors FLT3, KIT and PDGFR-β, Exhibits Powerful In Vivo Anti-Glioblastoma Activity

Malignant gliomas

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Nanorods Based on Mesoporous Silica Containing Iron Oxide Nanoparticles as Catalytic Nanomotors: Study of Motion Dynamics

Self‐propelled

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Bimodal Therapeutic Agents Against Glioblastoma, One of the Most Lethal Forms of Cancer

About 95 % of people...

3D Reduced Graphene Oxide Scaffolds with a Combinatorial Fibrous-Porous Architecture for Neural Tissue Engineering

Graphene oxide

...

Tris-pyridylmethylamine (TPMA) complexes functionalized with persistent nitronyl nitroxide organic radicals

The chance to

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